EFFECTS OF HIGH DOSED LONG ACTING OXYTETRACYCLINE ON SOME HAEMOTOLOGICAL INDICES IN GOATS

Authors

  • Z. A. Bhutto Faculty of Animal Husbandry and Veterinary Sciences, Sindh Agriculture University Tandojam, Pakistan
  • T. A. Qureshi Faculty of Animal Husbandry and Veterinary Sciences, Sindh Agriculture University Tandojam, Pakistan
  • S. Bughio Faculty of Animal Husbandry and Veterinary Sciences, Sindh Agriculture University Tandojam, Pakistan
  • S. A. Soomro Faculty of Animal Husbandry and Veterinary Sciences, Sindh Agriculture University Tandojam, Pakistan
  • M. Malhi Faculty of Animal Husbandry and Veterinary Sciences, Sindh Agriculture University Tandojam, Pakistan

Keywords:

Anaemia, goats, haemotology, immunity, oxytetracycline

Abstract

The present study assessed effects of high dosed long acting oxytetracycline (Oxy LA) on some haemotological indices in six goats. Each goat was intramuscularly administered with a high dose (30 mg/kg BW) of Oxy LA for the period of 07 days with an interval of 48 hours. The blood samples were taken at different time-points from 0-148 h after final dose of Oxy LA for the assessment of haemotological indices. The results showed that Oxy LA administration  significantly decreased (p< 0.05) leucocytes count at various time points from 6 to 120 h and the decrease in leucocyte count was highly significant (P< 0.01) at 72 and 96 h post-administration. Oxy LA treatment caused significant decrease (P< 0.05) in the lymphocytes count (1000/cu.mm)  at all observed time-points from 6 to 148 h and the decrease in lymphocyte count was highly significant (P< 0.01) at various time points from 12 to 120 h. Significant decrease in the RBC count (millions/cu.mm), haemoglobin concentration (g/dl) and packed cell volume (PCV, %) was recorded at 24, 120, 148 h (P< 0.05) and at 48, 72, 96 h (P< 0.01) after administration of high dosed Oxy LA. Maximum decrease in RBC count, haemoglobin level and PCV occurred at 72 h post-administration.

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Published

2015-06-30