EFFICACY OF VALBAZEN (ALBENDAZOLE) AGAINST GASTRO-INTESTINAL NEMATODES IN GOATS

Abstract

Efficacy of Valbazen against gastro-intestinal nematodes was evaluated in 48 naturally infected goats, divided into A and B groups (n=24 each), which were further sub-divided (n=8 each) into A-I and B-I (Pure Haemonchus contortus), A- II and B-II (mixed infection with H. contortus), and A-III and B-III (mixed infection without H. contortus). Group A, was treated with Valbazen, while group-B served as positive control. The eggs per gram (EPG) were determined at day zero, 3, 7, 10 and 14 post- treatment. The EPG counts significantly (P< 0.05) decreased from 4787.5 (day zero)  to 1425; and 543.8 in A-I, from 1050 to 350 and 125 in A-II and from 856.3 to 375 and 100 in A-III at day 10 and 14, respectively. The study indicated significant increase (P< 0.001) in PCV percentage at day 14, i.e., 29.19±1.5; 28.6 ± 2.4 and 27.1 ± 2.5, in group, A-I, A-II and A-III, respectively. The Hb concentration increased significantly in treated goats as compared to control group on day 14 post treatment.