EFFECT OF RECOMBINANT BOVINE SOMATOTROPIN TREATMENT ON HEMATOLOGICAL AND SERUM BIOCHEMICAL VARIABLES OF YOUNG KAMORI GOAT
Keywords:bovine somatotropin, goat, recombinant, thyroid, IGF-I
The present study was carried out on sixteen young goats of Kamori breed having age 9-10 weeks and weighing 14-15 kg body weight (BW). After an adaptation period of two weeks, goats were housed in the outerdoor pens (4 animals/pen) under ambient temperature and lighting. The animals were randomly divided into two groups, C and rbST. The animals in rbST group received intramuscular injection of rbST fortnightly, at the dose rate of 1 mg/kg. BW and those in C were kept as control. The experiment lasted for a period of 22 weeks. Animals were fed adlibitum the total mixed ration as a basal diet composed of roughages and concentrates (60:40), twice a day at 08:00 am and 05:00 pm and water was provided ad libitum. The hematological analysis of blood sampled on week 10 of experiment showed an increase (P < 0.05) in red blood cells (RBC) count and hemoglobin concentration in rbST treated goats than that of untreated goats, however, no significant effect (P< 0.05) of rbST was observed on hematological parameters in the blood of goats sampled on week 22 of the experiment. The serum total protein and glucose concentrations increased (P< 0.05) and the total lipid concentration decreased in goats of rbST group than that of control, however, no significant change (P< 0.05) was found in these variables on week 22 of the experiment. The serum IGF-I concentrations increased in the blood of rbST treated on week 10 and 22 of the experiment. The serum T3 concentration increased (P< 0.05) in rbST group than that of control on week 10 of trial but did not differ (P< 0.05) between the groups on week 22 of the trial. While the serum T4 concentration was not different (P< 0.05) between the group, on week 10 and 22 of the experiment. In conclusion, the present study reveals that rbST treatment stimulated eryhthropoises and increased serum concentrations of IGF-I and T3 in the blood of goats sampled on week 10.
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