EFFECT OF RECOMBINANT BOVINE SOMATOTROPIN TREATMENT ON HEMATOLOGICAL AND SERUM BIOCHEMICAL VARIABLES OF YOUNG KAMORI GOAT

Abstract

The present study was carried out on sixteen young goats of Kamori breed having age 9-10 weeks and weighing 14-15 kg body weight (BW). After an adaptation period of two weeks, goats were housed in the outerdoor pens (4 animals/pen) under ambient temperature and lighting. The animals were randomly divided into two groups, C and rbST. The animals in rbST group received intramuscular injection of rbST fortnightly, at the dose rate of 1 mg/kg. BW and those in C were kept as control. The experiment lasted for a period of 22 weeks. Animals were fed adlibitum the total mixed ration as a basal diet composed of roughages and concentrates (60:40), twice a day at 08:00 am and 05:00 pm and water was provided ad libitum. The hematological analysis of blood sampled on week 10 of experiment showed an increase (P < 0.05) in red blood cells (RBC) count and hemoglobin concentration in rbST treated goats than that of untreated goats, however, no significant effect (P< 0.05) of rbST was observed on hematological parameters in the blood of goats sampled on week 22 of the experiment. The serum total protein and glucose concentrations increased (P< 0.05) and the total lipid concentration decreased in goats of rbST group than that of control, however, no significant change (P< 0.05) was found in these variables on week 22 of the experiment. The serum IGF-I concentrations increased in the blood of rbST treated on week 10 and 22 of the experiment. The serum T₃ concentration increased (P< 0.05) in rbST group than that of control on week 10 of trial but did not differ (P< 0.05) between the groups on week 22 of the trial. While the serum T₄ concentration was not different (P< 0.05) between the group, on week 10 and 22 of the experiment. In conclusion, the present study reveals that rbST treatment stimulated eryhthropoises and increased serum concentrations of IGF-I and T₃ in the blood of goats sampled on week 10.